Is biofilm keeping you awake?
Biofilms can colonize CPAP tubing and medical devices, creating persistent microbial communities that are difficult to remove.
What is a biofilm?
A biofilm is a structured community of microorganisms embedded in a protective matrix. Unlike free-floating (planktonic) cells, biofilm-associated microbes adhere to surfaces and are far more resistant to cleaning and antimicrobial treatment.
Biofilms and CPAP equipment
CPAP machines deliver continuous airflow through plastic tubing and masks. Moisture, warmth, and organic material make these surfaces ideal for biofilm formation, potentially introducing microbes directly into the respiratory tract.
Why biofilms resist antibiotics
- Limited penetration of antibiotics through the matrix
- Altered gene expression compared to planktonic cells
- Horizontal gene transfer of resistance genes
The role of DNA sequencing
Next-generation sequencing reveals which microbes are present in biofilms and how gene regulation differs inside these communities, enabling deeper understanding of persistence and resistance.
Study biofilms at the molecular level
We support microbial genomics and biofilm research.