Whole genome sequencing for predicting cancer
Comprehensive genome-wide analysis reveals inherited and somatic risk factors for cancer development.
Whole genome sequencing (WGS) interrogates coding and non-coding regions, enabling detection of single nucleotide variants, structural variants, copy number changes, and regulatory mutations.
As sequencing costs decline, WGS is increasingly used to identify inherited cancer predisposition, refine risk assessment, and guide preventative screening strategies.
Large-scale cancer genome projects have already sequenced tens of thousands of tumors, accelerating discovery of novel cancer-associated genes.