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Bioinformatics

Bioinformatics that scales from single projects to full programs

MR DNA provides analysis across the full range of modern sequencing—genomes, transcriptomes, targeted panels, epigenetics, microbial ecology, and applied R&D. We focus on defensible methods, transparent QC, and outputs that are easy to use in publications, proposals, and product decisions.

Coverage
Human • Animal • Plant • Microbial
Data types
WGS • RNA-seq • Targeted • Meta
Deliverables
Reports • Figures • Data tables

Core analysis capabilities

A broad toolkit—so your analysis can match your question. We support standard workflows and custom designs.

Genomics & variants

From microbial isolates to complex genomes—QC, mapping, variant discovery, and interpretation-ready outputs.

  • Coverage, contamination, and QC summaries
  • SNP/indel/SV workflows (as appropriate)
  • Comparative genomics and phylogenomics

Assembly & annotation

De novo assembly and functional annotation with repeatable methods and clear deliverables.

  • Short/long-read assembly strategies
  • Gene calling and functional annotation
  • Reference builds and database support

RNA-seq & expression

Expression analysis that respects study design—mechanisms, response, and discovery programs.

  • Differential expression and QC
  • Enrichment / pathway interpretation
  • Time series and complex designs

Targeted panels

Focused workflows when you know what you’re looking for—amplicons, capture/enrichment, and custom targets.

  • Panel QC and on-target metrics
  • Variant/allele calling when applicable
  • Actionable reporting formats

Epigenetics & methylation

Methylation workflows for regulation and discovery (e.g., bisulfite-based approaches).

  • QC and alignment strategies
  • Differential methylation outputs
  • Project-specific reporting

Metagenomics & communities

Community and functional profiling for environmental, agricultural, and host-associated systems.

  • Amplicon and shotgun metagenomics
  • Functional profiling and pathway summaries
  • Genome-resolved options when appropriate

Industries & application areas

We work across research and product programs—so you’re not boxed into a niche.

  • Human health & oncology: tumor/normal studies, expression programs, biomarker discovery workflows
  • Agriculture & animal health: trait programs, pathogens, production systems, environmental impacts
  • Environmental & industrial: water/soil/sediment, bioprocess monitoring, bioremediation support
  • Microbial genomics: isolate comparisons, strain typing, comparative genomics
  • Public health & surveillance: pathogen genomics and outbreak-support analyses (project dependent)

What you receive

Designed for clarity and decision-making:

  • QC summary and key metrics
  • Primary result tables (variants / expression / taxonomy / pathways)
  • Publication-ready figures when requested
  • Methods and parameters summary
  • Optional: reproducible scripts/workflow notes

How projects run

A simple process that keeps scope clear and results defensible.

1) Define the outcome

Data type, sample count, study design, and the decision you need to make.

2) Run analysis + QC

Transparent QC gates and workflow choices aligned to your project.

3) Deliver & review

Clear reports, figures, and tables—plus optional iteration for manuscripts or internal reviews.

Tell us your data type—get a clear plan

Share sample counts and the research goal. We’ll recommend a workflow and provide a quote.