Ion S5 XL / PGM
Semiconductor sequencing platform. Note: this platform is discontinued at MR DNA and replaced by Illumina short-read platforms for most workflows.
Platform discontinued
Most Ion workflows have moved to Illumina MiSeq (targeted/amplicon) and
Illumina NovaSeq 6000 (high-throughput) for improved accuracy, standardization, and scale.
Historical Ion use cases
- Targeted gene panels and amplicons
- Small pilot studies
- Time-sensitive runs
Modern replacements
- MiSeq for targeted/amplicon workflows with flexible read lengths
- NovaSeq 6000 for high-throughput and large cohort studies
What to include in a request
- Sample type and count
- Assay goal (amplicon / panel / WGS / RNA)
- Target depth (reads per sample / coverage)
- Deliverables (FASTQ only vs analysis/report)
- Timeline
Need help selecting the right platform?
We’ll recommend the best platform for your depth, budget, and timeline.