Whole Genome Sequencing (WGS)
Scalable whole genome sequencing for microbes and complex genomes, with project scoping based on organism, genome size, and target coverage. High sample counts and higher data volumes qualify for volume discounts.
Genome Sequencing Services Built for Discovery and Scale
MR DNA supports whole genome sequencing for bacterial and fungal genomes, eukaryotic genomes, and targeted resequencing studies. Choose short-read WGS for cost-effective variant discovery, or long-read sequencing for de novo assembly and structural variant resolution.
Common Project Types
- De novo genome sequencing with assembly for novel organisms or reference creation
- Resequencing against a reference genome for SNP/indel and structural variant detection
- Microbial genomics for strain comparison, outbreak tracking, plasmids, and phage work
- Population / cohort studies with consistent coverage targets across samples
Typical Deliverables
- Raw data (FASTQ) and QC summaries
- Aligned files (BAM/CRAM) and variant files (VCF) when requested
- De novo assemblies (FASTA) and basic assembly statistics
- Optional annotation and bioinformatics reporting
Need a specific pipeline or format? We can scope outputs to match your downstream tools and publication requirements.
Genome Sequencing Pricing
Volume Discounts Available Larger projects reduce per-sample costs. We scope each project based on organism, genome size, target coverage, library type, and analysis needs.
Custom Quotes (Best Pricing)
All genome projects are quoted. MR DNA works with you to select the right platform, sequencing depth, and deliverables to meet your study goals efficiently.
Tip: include organism, genome size estimate, sample count, target coverage, and whether you need data only or analysis.
Short-Read WGS (Data Only Examples)
| Platform / Read Length | Output per Sample | Price |
|---|---|---|
| Illumina NovaSeq 6000 (2×150 bp) | 10M paired-end reads | $300 |
| Illumina NovaSeq 6000 (2×150 bp) | 30M paired-end reads | $400 |
| Illumina HiSeq (2×250 bp) | 10M paired-end reads | $400 |
| Illumina HiSeq (2×250 bp) | 4M paired-end reads | $300 |
| Illumina MiSeq (2×300 bp) | 1–2M paired-end reads | $500 |
* Examples shown for reference only. Final pricing depends on genome size, target coverage, library preparation method, and bioinformatics scope.
Long-Read Genome Sequencing
PacBio Sequel supports de novo assembly, structural variants, and complex regions that benefit from long reads.
Low-coverage bacterial genomes starting at $700.
Coverage depth, genome size, and assembly requirements determine final cost.
Additional technical details (legacy content)
From Bacterial and Fungal genome sequencing to human Whole Genome Sequencing (WGS), MR DNA has you covered!!
MR DNA has a wide array of NGS platforms to accomplish your sequencing goals, including the Illumina NovaSeq 6000 and the PacBio Sequel IIe.
Discounts are available for projects with > 5 genomes. Contact us for bulk discounts.
Benefits of Whole Genome Sequencing
One key benefit to choosing whole genome sequencing (WGS) over targeted sequencing methods is that WGS allows researchers an all-inclusive look at the genome in question. High-throughput sequencing enables detection of small and rare genetic mutations such as INDELs and SNPs. With increased sensitivity, WGS supports research across oncology, immunology, and many additional disciplines.
Whole genome sequencing is also powerful for bacterial, fungal, and other microbial organisms. Several microbial genomes can be sequenced in parallel, saving both time and money while maintaining strong depth.
References
Illumina.com (2019). Agriculture Throughout the World is Benefiting from the Latest NGS Technologies.
Pew Research Center (2019). World population growth is expected to nearly stop by 2100.
Ready to start a genome project?
Share organism, genome size, sample count, and goals — we’ll recommend depth, platform, and deliverables, and apply volume discounts where available.